Comparing Tumor Rates in Current and Historical Control Groups in Rodent Cancer Bioassays
نویسندگان
چکیده
منابع مشابه
Application of genomic biomarkers to predict increased lung tumor incidence in 2-year rodent cancer bioassays.
Rodent cancer bioassays are part of a legacy of safety testing that has not changed significantly over the past 30 years. The bioassays are expensive, time consuming, and use hundreds of animals. Fewer than 1500 chemicals have been tested in a rodent cancer bioassay compared to the thousands of environmental and industrial chemicals that remain untested for carcinogenic activity. In this study,...
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ژورنال
عنوان ژورنال: Statistics in Biopharmaceutical Research
سال: 2011
ISSN: 1946-6315
DOI: 10.1198/sbr.2010.09044